ADHD medications

If medication is right for you and your ADHD,
we’re here to help you get the treatment you need

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Preparing to treat your ADHD

Medication is one of many options to consider when exploring treatment for ADHD for both children and adults. To receive a prescription for ADHD medication, you’ll need a comprehensive assessment and diagnosis. Remember that while medication cannot cure ADHD, it can ease your symptoms and make a difference in your everyday life.

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Types of ADHD medication

There are generally two types of medication for ADHD: stimulants and non-stimulants. Each has its pros and cons, which means the best option for you and your treatment is based on your needs and preferences.

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Stimulant medications are the most widely used medications for the treatment of ADHD. Despite the name, these medications do not work by increasing the stimulation of the person directly. Instead, they help critical nerve networks in the brain communicate more effectively with one another. In some cases, the first medicine you try might not be the correct one, or a higher dose might be needed.

Common stimulant medications used to treat ADHD include methylphenidate, and dextroamphetamine (Dexedrine, Dextrostat). Methylphenidate and amphetamine are now available as both short- or long- acting prescriptions.

Here are a few of the most popular stimulant name-brand prescriptions:

  1. Adderall XR (amphetamine)
  2. Concerta (methylphenidate)
  3. Dexedrine (amphetamine)
  4. Evekeo (amphetamine)
  5. Focalin XR (dexmethylphenidate)
  6. Quillivant XR (methylphenidate)
  7. Ritalin (methylphenidate)
  8. Vyvanse (lisdexamfetamine dimesylate)
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Non-stimulants may be used when stimulant medications have been ineffective, in the case of unacceptable side effects, or if the patient prefers.

Unlike fast-acting stimulants, non-stimulant ADHD medications may take up to a week for full effectiveness.

Types of non-stimulant medications:

These non-stimulant ADHD medications were created to treat symptoms of ADHD and are approved by the U.S. Food and Drug Administration (FDA) as safe, proven treatments.

  1. Strattera (atomoxetine) was one of the first non-stimulant ADHD medications. Its generic name is atomoxetine. Strattera works similarly to selective serotonin reuptake inhibitors (SSRIs) that are used to treat depression by raising levels of the neurotransmitter norepinephrine in the brain. This can help the primary symptoms of ADHD: hyperactivity, impulsivity, and inattention.
  2. Intuniv (guanfacine) is a time-release version of the central alpha2A-adrenergic receptor agonist guanfacine. It is taken once daily and is thought to affect receptors in the brain in a way that improves ADHD symptoms such as hyperarousal, emotional sensitivity, and social aggression with limited side effects. It is not a controlled substance and has a low risk of abuse or dependence. 
  3. Kapvay (clonidine) is an extended-release alpha-agonist medication used to reduce blood pressure and relax blood vessels. It can also trigger the release of norepinephrine in the brain, which, in turn, can improve ADHD symptoms.

The most commonly prescribed antidepressant for ADHD is Wellbutrin.

  1. Wellbutrin (bupropion) is a norepinephrine dopamine reuptake inhibitor (NDRI), meaning it slows down the reabsorption of dopamine and norepinephrine after these chemicals are released to the brain. This action makes these neurotransmitters more available and ready to send messages in the brain. 
  2. Effexor XR (venlafaxine) is part of a newer class of antidepressant medications called serotonin-norepinephrine reuptake inhibitor (SNRI). It is sometimes, but not often, used to treat ADHD due to its increased levels of norepinephrine and serotonin in the brain, which can improve mood or concentration. 


Tricyclic antidepressants have been shown to improve ADHD symptoms for some patients who don’t respond to stimulants. The options include: 

  1. Tofranil (imipramine)
  2. Desipramine (Norpramin, Pertofrane)
  3. Nortriptyline (Aventyl, Pamelor).


There is the most evidence for ADHD symptom control with desipramine, but tricyclic antidepressants can cause side effects that some patients find to be intolerable.

The most common side effects of antidepressants are nausea and vomiting, weight gain, diarrhea, sleepiness, and sexual problems.  Wellbutrin XR and Effexor XR generally do not cause as many side effects as tricyclic antidepressants and MAOIs.

These medications have the same active ingredient as FDA-approved non-stimulant ADHD medications and can be used to help treat symptoms of ADHD.

  1. Clonidine (Catapres) is an alpha-agonist medication used to relax blood vessels and reduce blood pressure. The extended-release formulation, Kapvay (mentioned above), is FDA-approved to treat ADHD.
  2. Tenex (Guanfacine) is an immediate-release central alpha2A-adrenergic receptor agonist with the same active ingredient as Intuniv (mentioned above).
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Managing your ADHD prescriptions​​

Every person considering medication treatment for ADHD should first have a comprehensive assessment to clarify the diagnosis, identify other medical, psychological or learning problems that may be present with ADHD.

After the diagnosis has been declared, a treatment plan should be developed in consultation with your physician or other medical professional. In this planning session, the patient, family and medical professional can work together to consider the various options for treatment including prescriptions. If medication is going to be used as part of your treatment plan, the medical professional will prescribe a specific medication for you to begin taking.

The medication trial should be monitored very carefully, especially in the early weeks so needed adjustments can be made to the dose and timing of the prescription you are taking. If the first medication you tried is not helpful or produces unpleasant side effects, the medical professional  should make adjustments as needed. If the adjustments are not sufficient to bring a positive response, another medication option can be tried.

Most individuals with ADHD respond positively to any of the frequently used medications that help manage ADHD symptoms. Some patients respond highly to one more than another. If the first medication tried does not produce a satisfactory response, we recommend talking with your prescribing medical professional to get a different type of ADHD medication

Ultimately, success with ADHD prescriptions depends on a collaborative effort between you and your committed medical professional. Medication treatment without proper monitoring, appropriate education about ADHD, and other appropriate treatment interventions is often not enough to help. ADHD prescription failure can be caused by non-compliance or when patients do not take the medication as prescribed by their medical professional.

Parents of children with ADHD sometimes report that medication used during their child’s earlier years no longer works once their child reaches adolescence. This problem can be solved by speaking with your child’s prescribing medical professional and adjusting the dose or switching to another ADHD medication. 

ADHD prescriptions can be a powerful tool in your tool belt for managing symptoms of ADHD. We encourage all patients to be open and honest with their doctor during the duration of taking any medication.

The national stimulant medication shortage continues to make it difficult to fill prescriptions in a timely manner. We understand many of our patients are struggling with their care due to the shortage.

We are doing everything we can to ensure you get the care you need, including offering ways for you to advocate for yourself.

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