Open-access publication demonstrates the validity and reliability of the Mentavi online Diagnostic Evaluation compared to a clinical interview, widening evidence-based telehealth access for adults with ADHD

GRAND RAPIDS, Mich., September 11, 2025 — Mentavi Health announced that its landmark, real-world validation study of the Mentavi Diagnostic Evaluation has been published in the peer-reviewed Journal of Clinical Psychiatry (JCP), a widely read and respected journal. The open-access article demonstrates that Mentavi’s asynchronous, online evaluation is as accurate as a traditional face-to-face clinical interview in the diagnosis of attention-deficit / hyperactivity disorder (ADHD) in adults and provides the first peer-reviewed evidence base for a fully digital diagnostic pathway for adult ADHD. The article posted on Psychiatrist.com at 8:00 am Central time on September 8, 2025 (see link and DOI below).

Key findings from the study¹

• n = 345 adults seeking web-based ADHD assessment (predominantly female; mean age = 35).
• Sensitivity = 80.6% and Positive Predictive Value = 94.9%
• False-positive rate = 12% versus 56% for the in-person clinical interview, indicating the online tool is accurate in diagnosing ADHD in adults
• Note: the full article is freely available via JCP (DOI below).

Executive comments

“Publication in a top-tier peer-review journal moves this evidence base forward, for our diagnostic evaluation specifically and for telehealth in general,” said Barry K. Herman, MD, MMM, Chief Medical Officer at Mentavi Health and first author of the paper. “The study shows that an online ADHD diagnosis can be accurately assessed asynchronously, closing gaps in care created by specialist shortages and long waitlists.”

“This study shows that online, asynchronous ADHD assessments can match the rigor of traditional interviews while expanding access for adults who face long wait times,” said Andrew J. Cutler, MD, Chief Medical Officer at Neuroscience Education Institute and Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University, and study co-author. “It demonstrates accuracy, reduces concerns about overdiagnosis, and advances evidence-based care for underserved groups.”

“Publication in JCP sets a new standard for evidence-based digital mental health,” added Keith Brophy, CEO of Mentavi Health. “It validates years of work to build the most rigorous online diagnostic platform and expands our mission to remove barriers of access to accurate mental-health assessments.”

Study design

The prospective, real-world observational study compared the Mentavi Diagnostic Evaluation—a self-paced, asynchronous questionnaire interpreted by a doctorate-level psychologist—with a structured face-to-face clinical interview conducted via video. Primary endpoints were sensitivity, specificity, and positive predictive value relative to DSM-5 criteria. The protocol was IRB-approved and powered to detect ≥80 % sensitivity with 95 % confidence.

Clinical and Public-Health Implications

• Pent-up demand: An estimated 17 million American adults have ADHD, yet waiting lists for specialist evaluation can exceed six months.
  
• Telehealth preference: CDC data indicate 46% of U.S. adults with ADHD already use telehealth services. Until now, no online assessment had been validated.
  
• Health-equity impact: Digital, asynchronous tools remove geographic and scheduling barriers, enabling evidence-based diagnosis for rural, underserved, and shift-working populations.
  

Article details (for authors)

• Journal: The Journal of Clinical Psychiatry
• Article title (final): Validity of an Online Assessment of Attention‑Deficit/Hyperactivity Disorder Among a Real‑World Sample of Adults Seeking Web‑Based Mental Health Care
• Byline: Barry K. Herman, MD, MMM; Stephen V. Faraone, PhD; Andrew J. Cutler, MD; Jeffrey H. Newcorn, MD; Emily M. LaFrance, PhD; Michelle Ripper Lewis, BSN, RN; Charles Ruetsch, PhD
• Citation: J Clin Psychiatry. 2025;86(3):25m15846
• DOI: 10.4088/JCP.25m15846
• URL: https://www.psychiatrist.com/jcp/Validity-Online-ADHD-Assessment-Real-World-Sample-Adults-Seeking-Web-Based-Mental-Healthcare

About Mentavi Health

Established as ADHD Online in 2018, Mentavi Health has evolved to encompass a broader range of mental health services. With the mission to make high-quality ADHD assessments accessible to all, Mentavi has grown to address not only ADHD but also the most common related mental health conditions. The nationwide Mentavi Mental Health Diagnostic Evaluation and various treatment options showcase the company’s commitment to providing comprehensive, accessible, compliant online mental health care. For more information, visit mentavi.com.

Media contact

Tim Cox, ZingPR for Mentavi Health
[email protected] 

¹ Additional statistics, subgroup analyses, and methodological details are available in the open-access article (Journal of Clinical Psychiatry, on September 8, 2025 (J Clin Psychiatry 2025;86(3):25m15846; doi:10.4088/JCP.25m15846).